3-Carboxy-5-chlorobenzotrifluoride, 5-Chloro-alpha,alpha,alpha-trifluoro-m-toluic acid
3-Chloro-5-(trifluoromethyl)benzoic acid
CAS: 53985-49-2
Molecular Formula: C8H4ClF3O2
3-Carboxy-5-chlorobenzotrifluoride, 5-Chloro-alpha,alpha,alpha-trifluoro-m-toluic acid - Names and Identifiers
| Name | 3-Chloro-5-(trifluoromethyl)benzoic acid |
| Synonyms | QVR CG EXFFF 3-Chloro-5-carboxybenzotrifluoride 3-Chloro-5-(trifluoromethyl)benzoic acid 3-CHLORO-5-(TRIFLUOROMETHYL)BENZOIC ACID Benzoic acid, 3-chloro-5-(trifluoromethyl)- 3-Carboxy-5-chlorobenzotrifluoride, 5-Chloro-alpha,alpha,alpha-trifluoro-m-toluic acid |
| CAS | 53985-49-2 |
| InChI | InChI=1/C8H4ClF3O2/c9-6-2-4(7(13)14)1-5(3-6)8(10,11)12/h1-3H,(H,13,14) |
3-Carboxy-5-chlorobenzotrifluoride, 5-Chloro-alpha,alpha,alpha-trifluoro-m-toluic acid - Physico-chemical Properties
| Molecular Formula | C8H4ClF3O2 |
| Molar Mass | 224.56 |
| Density | 1.523 |
| Melting Point | 98-101℃ |
| Boling Point | 263℃ |
| Flash Point | 113℃ |
| Water Solubility | Soluble in water. |
| Vapor Presure | 0.00548mmHg at 25°C |
| Storage Condition | Sealed in dry,Room Temperature |
| Refractive Index | 1.495 |
3-Carboxy-5-chlorobenzotrifluoride, 5-Chloro-alpha,alpha,alpha-trifluoro-m-toluic acid - Introduction
3-Chloro-5-(trifluoromethyl)benzoic acid is an organic compound with the chemical formula C8H4ClF3O2. The following is a description of its nature, use, formulation and safety information:
Nature:
-Appearance: 3-Chloro-5-(trifluoromethyl)benzoic acid is a colorless or slightly yellow solid.
-Solubility: It has good solubility in common organic solvents, such as ethanol, dimethylformamide, etc.
-Melting point: about 158-159 ℃.
-Stability: It is relatively stable at room temperature and relatively stable in light and humid environments.
Use:
- 3-Chloro-5-(trifluoromethyl)benzoic acid is commonly used as a reagent in organic synthesis, for example, as a protecting group of benzoic acid, to adjust the selectivity of the reaction.
-It can also be used to prepare other organic compounds, such as 3-chloro-5-trifluoromethylbenzoyl chloride.
Preparation Method:
- 3-Chloro-5-(trifluoromethyl)benzoic acid can be obtained by reacting p-anisole with N-chloroformamide, and then deprotected with trifluoroacetic acid to obtain the target product.
Safety Information:
- 3-Chloro-5-(trifluoromethyl)benzoic acid is an organic acid and follows safe practices for general organic acids.
-It may cause irritation to the eyes, skin and respiratory tract and direct contact should be avoided.
-in the use of the process should pay attention to protective measures, such as wearing protective glasses, gloves, rubber shoes, etc.
-During storage and handling, it should be stored separately from oxidants and strong alkali substances to avoid dangerous reactions.
-If ingested or inhaled, please seek medical treatment.
Nature:
-Appearance: 3-Chloro-5-(trifluoromethyl)benzoic acid is a colorless or slightly yellow solid.
-Solubility: It has good solubility in common organic solvents, such as ethanol, dimethylformamide, etc.
-Melting point: about 158-159 ℃.
-Stability: It is relatively stable at room temperature and relatively stable in light and humid environments.
Use:
- 3-Chloro-5-(trifluoromethyl)benzoic acid is commonly used as a reagent in organic synthesis, for example, as a protecting group of benzoic acid, to adjust the selectivity of the reaction.
-It can also be used to prepare other organic compounds, such as 3-chloro-5-trifluoromethylbenzoyl chloride.
Preparation Method:
- 3-Chloro-5-(trifluoromethyl)benzoic acid can be obtained by reacting p-anisole with N-chloroformamide, and then deprotected with trifluoroacetic acid to obtain the target product.
Safety Information:
- 3-Chloro-5-(trifluoromethyl)benzoic acid is an organic acid and follows safe practices for general organic acids.
-It may cause irritation to the eyes, skin and respiratory tract and direct contact should be avoided.
-in the use of the process should pay attention to protective measures, such as wearing protective glasses, gloves, rubber shoes, etc.
-During storage and handling, it should be stored separately from oxidants and strong alkali substances to avoid dangerous reactions.
-If ingested or inhaled, please seek medical treatment.
Last Update：2024-04-10 22:29:15
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Product Name: 3-CHLORO-5-(TRIFLUOROMETHYL)BENZOIC ACID Visit Supplier Webpage Request for quotation
CAS: 53985-49-2
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
CAS: 53985-49-2
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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